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Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient
Katie A Dunleavy1, Ryan C Ungaro2, Laura Manning2
1Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Background:
Micronutrient deficiencies are common in patients with inflammatory bowel disease (IBD). To date, the literature has focused on vitamin D, vitamin B12, and iron deficiencies.
Methods:
We report a case series of 20 patients with IBD and vitamin C deficiency treated at a single tertiary care center.
Results:
Sixteen (80%) patients had symptoms of clinical scurvy, including arthralgia, dry brittle hair, pigmented rash, gingivitis, easy bruising, and/or brittle nails. Eighteen patients underwent a nutritional assessment, 10 (56%) patients reported complete avoidance of fruits and vegetables, and 3 (17%) reported reduced intake of fruits and vegetables.
Conclusions:
Vitamin C deficiency should be considered in IBD patients, particularly those with reduced fruit/vegetable intake, as it can lead to significant signs and symptoms.
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