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Published on: February 1, 2012
Defining Research Priorities in Nutrition and Inflammatory Bowel Disease: Insights From the Nutrition and IBD
Stephanie Gold1, Andrew S Day2, Eytan Wine3
1The Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York.
Background & Aims:
In the past decade, studies have identified an association between nutrition and the pathogenesis and progression of inflammatory bowel disease as well as the utility of diet as a potential treatment strategy. Despite the growing interest, the current research gaps and priorities have yet to be defined.
Methods:
The Nutrition and IBD Research Group is an international working group including 35 adult and pediatric gastroenterologists and dietitians with expertise in nutrition and inflammatory bowel disease research. After defining relevant subdomains within the field of nutrition research, working groups identified research gaps/priorities within each area supported by evidence review. Nutrition and IBD Research Group members independently rated the priority of each statement (1 [highest] to 9 [lowest]) within each domain. The highest priority statements (<4) were included for review/modification. A second independent round of rating was done by all Nutrition and IBD Research Group members.
Results:
The Nutrition and IBD Research Group identified 7 key domains: Diet as a Treatment for Inflammatory Bowel Disease, Dietary Epidemiology, Malnutrition, Sarcopenia and Obesity, Eating Behaviors and Quality of Life, Implementation of Dietary Trials, Translational Nutrition Research, and Best Practices for Nutrition Research and Study Design. A total of 50 research gaps and priorities were developed. Thirty-four of 35 Nutrition and IBD Research Group members (97%) completed the first rating. After full group review and statement modification to remove repetition and improve clarity, a total of 39 statements were included.
Conclusions:
Based on expert consensus, this study identified knowledge gaps and research priorities related to nutrition and inflammatory bowel disease. These gaps, priorities, and best practices will be used to frame future research studies and funding proposals to advance the field.
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