Thoracic computed tomography in the progressive fibrotic phenotype
Anand Devaraj1, Gianluca Milanese2, Nicola Sverzellati2
1Department of Radiology, Royal Brompton Hospital, London, UK. National Heart and Lung Institute, Imperial College, London, UK.
Current Opinion in Pulmonary Medicine
|July 5, 2021
Summary
Determining progressive lung fibrosis using serial thoracic computed tomography (CT) is crucial for patient treatment. This review covers methods, parameters, and challenges for accurately assessing fibrotic lung disease progression via CT scans.
Area of Science:
- Pulmonary Medicine
- Radiology
- Medical Imaging
Background:
- Progressive lung fibrosis requires accurate identification for optimal treatment strategies.
- Serial high-resolution computed tomography (CT) is a key imaging modality for monitoring disease progression.
- Understanding CT-based markers is essential for managing fibrotic lung diseases.
Purpose of the Study:
- To review the rationale and methodologies for detecting progressive lung fibrosis on thoracic CT.
- To describe the limitations and challenges associated with CT-based fibrosis assessment.
- To inform clinicians and radiologists on optimal CT interpretation for fibrotic lung disease.
Main Methods:
- Review of current literature on thoracic CT for progressive lung fibrosis.
- Analysis of visual and automated parameters used to assess disease progression on CT.
- Evaluation of studies exploring CT's role in monitoring fibrotic lung disease.
Main Results:
- Various visual and automated CT parameters can signify progressive fibrosis.
- Serial CT is a viable method for determining disease progression in fibrotic lung disease.
- Awareness of optimal methods and limitations is necessary for reliable CT interpretation.
Conclusions:
- Reliable use of serial CT for disease progression requires understanding optimal assessment methods.
- Clinicians and radiologists must be aware of CT interpretation limitations in fibrotic lung disease.
- Accurate CT assessment aids in determining appropriate treatment for progressive lung fibrosis.
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