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Updated: Aug 11, 2026
Routine Screening Method for Microparticles in Platelet Transfusions
Published on: January 31, 2018
A Quality Approach to Reducing the Occurrence of Occluded Leukocyte Reduction Filters During Platelet Transfusion
Cory Wongsa1, Nava Ghiyassi, Marah Cornelius
1Hemovigilance Unit, The University of Texas M.D. Anderson Cancer Center, Main Campus, Houston.
Background:
In 2019, an increase in clotted platelet filter occurrences was noted with the implementation of new leukocyte reduction filters through a volumetric pump.
Local Problem:
Occluded platelet filters contribute to delays in platelet transfusions, additional nursing workflows, and potential wastage of platelets, leading to staff and patient dissatisfaction.
Methods:
Direct observation of nursing practice with priming platelet filters identified opportunities for improvement. Education was designed incorporating manufacturer recommendations with results of the observations. Nursing education was disseminated through small group sessions, one-to-one teaching, tip sheets, and an e-learning video.
Results:
Nursing education interventions resulted in a 170% reduction in the reported monthly filter occlusion rate.
Conclusion:
Engagement of nurses in quality improvement processes and collaboration across departments led to a sustained decrease in the clotted platelet filters.
