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Updated: Oct 30, 2025

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins
Published on: August 31, 2019
Liposome composition in drug delivery design, synthesis, characterization, and clinical application
Danielle E Large1, Rudolf G Abdelmessih1, Elizabeth A Fink1
1Department of Chemical Engineering, Northeastern University, 360 Huntington Ave., Boston, MA 02115, USA.
Abstract:
Liposomal drug delivery represents a highly adaptable therapeutic platform for treating a wide range of diseases. Natural and synthetic lipids, as well as surfactants, are commonly utilized in the synthesis of liposomal drug delivery vehicles. The molecular diversity in the composition of liposomes enables drug delivery with unique physiological functions, such as pH response, prolonged blood circulation, and reduced systemic toxicity. Herein, we discuss the impact of composition on liposome synthesis, function, and clinical utility.
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