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Heart failure following transcatheter aortic valve replacement
Vassili Panagides1, Alberto Alperi1, Jules Mesnier1
1Department of Cardiology, Quebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada.
Expert Review of Cardiovascular Therapy
|July 6, 2021
Summary
Heart failure (HF) decompensation is a major cause of hospital readmission after transcatheter aortic valve replacement (TAVR). Addressing pre-existing conditions and post-procedure complications is crucial for reducing HF events in TAVR patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Heart Failure Management
Background:
- Transcatheter aortic valve replacement (TAVR) procedures have surged in popularity.
- Despite TAVR advancements, high hospital readmission rates persist, primarily due to heart failure (HF) decompensation.
Purpose of the Study:
- To review the current landscape of HF following TAVR.
- To examine HF incidence, clinical impact, risk factors, and therapeutic strategies post-TAVR.
Main Methods:
- This study is a comprehensive literature review.
- It synthesizes current evidence on heart failure after TAVR.
Main Results:
- HF decompensation is the leading cause of TAVR rehospitalization, linked to poor prognosis.
- Pre-existing conditions (e.g., cardiac amyloidosis, pulmonary hypertension) and post-procedural issues (e.g., paravalvular leaks, prosthesis-patient mismatch) increase HF risk.
Conclusions:
- Reducing HF events post-TAVR necessitates a multidisciplinary approach.
- Optimizing medical treatment, managing residual valvular disease, and addressing conduction disturbances are key.
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