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Related Experiment Videos

Uncombable-hair syndrome.

W L Matis1, H Baden, R Green

  • 1Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore MD 21205.

Pediatric Dermatology
|November 1, 1987
PubMed
Summary
This summary is machine-generated.

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Uncombable hair syndrome (UHS) is a rare genetic condition causing hair that is difficult to manage. Diagnosis is confirmed by electron microscopy showing characteristic longitudinal grooves in the hair shaft.

Area of Science:

  • Dermatology
  • Genetics
  • Pediatrics

Background:

  • Uncombable hair syndrome (UHS) is a rare disorder affecting hair structure.
  • It is characterized by hair that is difficult to brush or comb.

Observation:

  • Four children presented with short, unmanageable, pale blond hair.
  • No other abnormalities or family history of hair disorders were noted.

Findings:

  • Light microscopy was normal in three children; pili torti was observed in one.
  • Electron microscopy revealed distinctive longitudinal grooves on the hair shaft in all four patients, confirming UHS.

Implications:

  • This study highlights the diagnostic utility of electron microscopy for uncombable hair syndrome.

Related Experiment Videos

  • Early diagnosis can aid in managing patient expectations and potential cosmetic concerns.