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A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies
Published on: July 28, 2020
Cost Variance in Patients With Soft Tissue Sarcoma Who Develop Postoperative Wound Complications
Benjamin K Wilke1, Jeannie Buckner, Maria T Huayllani
1From the Department of Orthopedic Surgery, Mayo Clinic, Jacksonville, FL (Dr. Wilke, Dr. Buckner, Dr. Murray, and Dr. Forte); the Division of Plastic Surgery, Mayo Clinic (Dr. Huayllani and Dr. Forte); and Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic (Dr. Huayllani, Dr. Spaulding, and Dr. Forte).
Background:
Wound complications after a soft-tissue sarcoma surgery are common, occurring in up to 30% to 40% of patients who undergo preoperative radiation therapy. Although risk factors for developing complications are well-known, there is a paucity of literature on the increased healthcare costs after a wound complication. The purpose of this study was to detail these additional costs after a soft-tissue sarcoma surgery.
Methods:
A retrospective review of 99 patients from January 2013 to October 2019 was performed. Hospital and professional charges for the primary surgical procedure and any subsequent hospitalization or procedure related to a wound complication were compiled. Costs were inflated to 2019 dollars.
Results:
Total costs were 21.3% higher for patients who developed a wound complication (P = 0.006). Most patients (32 of 42; 76.2%) who developed a complication required a return trip to the operating room. The average number of return trips was 1.2 (range 0 to 5). For each return trip to the operating room because of a wound complication, an associated increased overall cost of 13.2% was noted (P < 0.001).
Conclusion:
Wound complications after a soft-tissue sarcoma resection are common and add considerable expense to the episode of care. A reduction in wound complications may markedly decrease the cost of treating soft-tissue sarcomas and continues to be an opportunity for improvement.
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