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Mesenteric Inflammatory Myofibroblastic Tumor on 68Ga-FAPI PET/CT
Huipan Liu1, Xiao Yang, Dongmei Fan
1From the Department of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University; Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province; and Academician (Expert) Workstation of Sichuan Province, Luzhou, Sichuan, China.
This study details the 68Gallium-fibroblast activation protein inhibitor (68Ga-FAPI) PET/CT imaging of an uncommon inflammatory myofibroblastic tumor in the mesentery. Findings highlight FAPI PET/CT as a potential diagnostic tool for this rare neoplasm.
Area of Science:
- Oncology
- Nuclear Medicine
- Radiology
Background:
- Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal neoplasm with diverse locations.
- Accurate diagnosis and staging of IMT can be challenging due to its uncommon nature and varied presentation.
Observation:
- A 49-year-old male patient presented with a mesenteric mass.
- Diagnostic imaging was performed using 68Gallium-fibroblast activation protein inhibitor (68Ga-FAPI) Positron Emission Tomography/Computed Tomography (PET/CT).
Findings:
- The 68Ga-FAPI PET/CT scan revealed characteristic uptake patterns in the mesenteric mass, consistent with inflammatory myofibroblastic tumor.
- FAPI PET/CT demonstrated high tumor-to-background ratio, aiding in lesion delineation and characterization.
Implications:
- This case suggests that 68Ga-FAPI PET/CT may be a valuable imaging modality for the diagnosis and management of inflammatory myofibroblastic tumors.
- Further research is warranted to establish the role of FAPI PET/CT in the broader clinical context of IMT.
![Automated Preparation of [68Ga]Ga-3BP-3940 on a Synthesis Module for PET Imaging of the Tumor Microenvironment](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F68356.jpg&w=3840&q=50)
