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Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
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Updated: Oct 29, 2025

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model
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Transient Cardiac Dysfunction Following a Cerebrovascular Accident.

Steven Hamilton1, Rana A Tauseen1, Sara L Wallach1

  • 1Internal Medicine, Jersey Shore University Medical Center/Saint Francis Medical Center Program, Trenton, USA.

Cureus
|July 9, 2021
PubMed
Summary
This summary is machine-generated.

Cerebral T-waves, a rare ECG finding of deep T-wave inversion, can mimic cardiac events after acute brain injury. This case highlights the importance of considering neurological causes for seemingly cardiac symptoms.

Keywords:
cardiac arrythmiacerebral t wavescerebro-vascular accident (stroke)left ventricular systolic dysfunctiont-waves

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Area of Science:

  • Neurocardiology
  • Neurology
  • Cardiology

Background:

  • Acute cerebral injuries frequently cause electrocardiogram (ECG) abnormalities, including arrhythmias and T-wave changes.
  • Cerebral T-waves are a rare, specific ECG phenomenon characterized by transient, symmetric, deeply inverted T-waves in precordial leads, often associated with acute ischemic stroke.

Observation:

  • A patient presented with symptoms suggestive of an ischemic cardiac event: acute pulmonary edema, precordial T-wave inversions, and left ventricular dysfunction.
  • Initial cardiac workup raised suspicion for myocardial infarction, but subsequent brain imaging revealed an acute cerebral injury.

Findings:

  • The patient's presentation mimicked a primary cardiac event, but the underlying cause was a neurological deficit.
  • This case underscores the potential for cerebral T-waves to be misdiagnosed as primary cardiac ischemia.

Implications:

  • Recognizing cerebral T-waves is crucial for accurate diagnosis and appropriate management of patients with acute neurological events.
  • This phenomenon highlights the complex interplay between the brain and the heart, emphasizing the need for a comprehensive diagnostic approach.