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Relation Between Cancer and Vasospastic Angina.
Tadahiro Matsumoto1, Yuichi Saito2, Kan Saito1
1Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
Advances in Therapy
|July 9, 2021
Summary
This study found no significant link between cancer history and vasospastic angina (VSA) diagnosis. Cancer treatments like chemotherapy and radiotherapy also did not show a significant association with VSA.
Area of Science:
- Cardiology
- Oncology
Background:
- Cancer patients face higher cardiovascular disease risks.
- Anticancer therapies can cause endothelial injury and vasospasm.
- The link between vasospastic angina (VSA) and cancer is understudied.
Purpose of the Study:
- To investigate the association between active cancer, cancer history, and VSA.
- To evaluate the impact of cancer type and treatment on VSA.
Main Methods:
- 786 patients underwent intracoronary acetylcholine (ACh) provocation tests for VSA diagnosis.
- Patients were categorized into active cancer, history of cancer, or no cancer groups.
- The study assessed correlations between cancer status, treatment, and positive ACh test results.
Main Results:
- No significant difference in VSA rates was observed between cancer patients (active or history) and those without cancer.
- Cancer type and treatments (chemotherapy, radiotherapy) did not significantly impact VSA diagnosis.
- The overall VSA diagnosis rate was 51.0% across all patient groups.
Conclusions:
- This study found no association between active cancer or a history of cancer and VSA diagnosis.
- Anticancer treatments, including chemotherapy and radiotherapy, were not significantly linked to positive ACh provocation tests for VSA.
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