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Updated: Oct 29, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
Hashimoto's thyroiditis aggravated by goitrogenic diet presenting as rhabdomyolysis worsened by alcohol intake
Robin George Manappallil1, Rajesh Muralidharan2, Sneha Shalu3
1Internal Medicine, Baby Memorial Hospital, Calicut, Kerala, India drrobingeorgempl@gmail.com.
Abstract:
Hashimoto's thyroiditis (HT) is the most common form of primary hypothyroidism. Several muscular manifestations like pain, weakness, stiffness and elevated muscle enzymes have been noticed in hypothyroidism. Alcohol is also known to cause myositis and rhabdomyolysis. Patients with thyroid should avoid certain foods like broccoli, cauliflower and cabbage as they contain goitrogens. This is a case of a young man who presented with severe muscle aches and pain and was found to have rhabdomyolysis. Further evaluation revealed an underlying HT. Moreover, he had been consuming raw broccoli, which is goitrogenic, and alcohol which worsened the rhabdomyolysis. He was managed with levothyroxine and intravenous fluids, following which he improved.
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