Anal adenocarcinoma: case report, literature review and comparative survival analysis
Cynthia J Tsay1,2, Thomas Pointer3, Jocelyn B Chandler4,5
1Medicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, Connecticut, USA.
Introduction:
Anal adenocarcinoma is a rare malignancy with a poor prognosis.
Methods:
We present a case of rare anal adenocarcinoma in a patient with normal screening colonoscopy. Using the Surveillance, Epidemiology and End Result database between 2000 and 2016, we performed survival analysis among individuals>20 years old comparing anal and rectal cancers.
Results:
Survival analysis showed that anal adenocarcinoma is associated with worse outcomes compared with rectal adenocarcinoma and anal squamous cell carcinoma.
Discussion:
This case and survival data illustrate the importance of prompt investigation of symptoms irrespective of colorectal cancer screening status with careful attention to examination of the anal area.
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