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A comparative study on cephalometric differences in maxillofacial morphology between skeletal Class III cases with
Atsushi Tanaka1, Noriaki Shoji2, Ikuho Kojima1
1Division of Dental Informatics and Radiology, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Japan.
Oral Radiology
|July 10, 2021
Summary
Acromegaly in patients with skeletal Class III malocclusion presents with increased mandibular ramus height and distinct labial inclination of mandibular incisors. This incisor inclination is key to differentiating acromegaly from non-acromegalic Class III malocclusion.
Area of Science:
- Orthodontics
- Endocrinology
- Medical Imaging
Background:
- Acromegaly commonly manifests with mandibular protrusion, a feature shared with skeletal Class III malocclusion.
- Differentiating acromegaly from non-acromegalic skeletal Class III malocclusion is crucial for appropriate patient management.
Purpose of the Study:
- To compare maxillofacial morphology between acromegaly patients and non-acromegalic skeletal Class III patients using cephalometric analysis.
- To identify specific cephalometric features that can distinguish acromegaly from skeletal Class III malocclusion.
Main Methods:
- Retrospective cephalometric analysis of 37 acromegaly (Acro) patients, 37 skeletal Class III (C-III) patients, and 37 Class I (C-I) control patients.
- Inclusion of linear and angular measurements, facial profilograms, and Receiver Operating Characteristic (ROC) curve analysis for diagnostic performance.
Main Results:
- The acromegaly group exhibited significantly larger mandibular ramus height compared to both Class III and Class I groups.
- A notable increase in the labial inclination of mandibular central incisors (L1/MP) was observed in the acromegaly group.
- ROC analysis identified an L1/MP cutoff of 88.4° with high diagnostic accuracy for differentiating acromegaly from non-acromegalic Class III malocclusion.
Conclusions:
- Acromegaly is associated with greater bimaxillary prognathism than non-acromegalic Class III malocclusion.
- The labial inclination of mandibular central incisors (L1/MP) is the most effective cephalometric indicator for distinguishing acromegaly from non-acromegalic Class III malocclusion.
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