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[Endotoxicosis in surgery].

P K D'iachenko, N M Zhelvakov

    Vestnik Khirurgii Imeni I. I. Grekova
    |July 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    General toxemia in acute surgery is a significant issue, often stemming from infection and pathological foci. Effective treatment requires addressing the root cause and employing various supportive therapies.

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    Area of Science:

    • Surgical pathology
    • Toxicology
    • Internal medicine

    Context:

    • Acute surgical conditions
    • Diffuse peritonitis
    • Sepsis
    • Thyrotoxicosis

    Purpose:

    • To highlight general toxemia as a critical problem in acute surgery.
    • To identify pathological foci as the primary cause of diffuse peritonitis and toxemia.
    • To discuss management strategies for toxemia in surgical patients.

    Summary:

    • General toxemia is a key concern in acute surgical settings, beyond just infection.
    • Pathological foci, such as diseased organs, are identified as the main drivers of diffuse peritonitis and systemic toxemia.
    • The study reviews cases including sepsis and severe thyrotoxicosis (Basedowian goiter).

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  • Recommended treatments include antibacterial therapy, fresh blood transfusion with heparin, forced diuresis, peritoneal dialysis, hemosorption, and ganglionic blockade.
  • Active surgical intervention to eliminate the pathological focus is crucial for managing general toxemia.

    • Impact:

    • Emphasizes the need for prompt surgical intervention to resolve the underlying pathological cause of toxemia.
    • Suggests a multimodal approach to managing severe toxemia in surgical patients.
    • Informs clinical practice regarding the comprehensive management of acute surgical toxemia.