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Local Anesthetic Lidocaine and Cancer: Insight Into Tumor Progression and Recurrence

Caihui Zhang1, Cuiyu Xie1, Yao Lu1,2

  • 1Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.

Frontiers in Oncology
|July 12, 2021
PubMed

Keywords:
cancerlidocainemetastasismolecular mechanismsrecurrencesurgerytumor

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While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
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