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Published on: April 28, 2019
Vitamin D Intoxication Presenting as Subacute Encephalopathy-A Case Report
Naik Tripty1, Jagzape Tushar1, Jondhale Sunil1
1Department of Paediatrics, All India Institute of Medical Sciences, Raipur, Raipur (Chhattisgarh), India.
Insights
Vitamin D intoxication in children, though rare, can cause severe symptoms. Prompt treatment with hydration and medication helped a 14-month-old infant recover from hypercalcemia and regain developmental milestones.
Area of Science:
- Pediatrics
- Endocrinology
- Toxicology
Background:
- Vitamin D intoxication is uncommon in pediatric populations.
- Manifestations range from mild gastrointestinal issues to severe neurological and cardiac complications.
- Often linked to excessive intake of vitamin D supplements.
Abstract:
Vitamin D intoxication is uncommon in children and is more commonly suspected in the setting of ingestion of high doses of vitamin D. Its manifestations can be non specific and varied ranging from mild like constipation and vomiting to life threatening like arrhythmias and encephalopathy. Here we present a 14 month female who presented with loss of milestones, floppiness, and poor interaction with mother. She was detected to have hypercalcemia and was subsequently diagnosed with vitamin D intoxication. She was successfully treated with hydration, furosemide, prednisolone and frequent monitoring of electrolytes, electrocardiography and volume status. Subsequently as her serum calcium levels normalized with therapy, she became alert, conscious and started achieving developmental milestones.
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