Comparative investigations about three different identification systems for Campylobacter pyloridis from human antrum...

Campylobacter pyloridis (C. p.) which was first isolated in 1983 in Australia by Marshall and Warren from human gastric mucosa has since been associated with chronic gastritis and ulceration of stomach and duodenum. A typical characteristic of this microorganism is very strong urease formation. Therefore, from the appearance of that enzyme in the gastric mucosa colonization with C. p. can be inferred. The investigations reported here were done to compare the cultivation of C. p. as a direct proof of the presence of this microorganism with two different enzymatic procedures to be used as a rapid indirect method for demonstration of the presence of C. p. A total of 100 patients were involved. The results show rather good agreement between all three procedures used (80%), so that, at least for epidemiological surveys, the demonstration of urease may be used as an indirect procedure for the demonstration of the presence of C. p.