Poly (red DSBR)/Al-ZnO modified carbon paste electrode sensor for dopamine: a voltammetric study

Area of Science:

• Materials Science
• Electrochemistry
• Analytical Chemistry

Background:

• Developing sensitive and selective electrochemical sensors is crucial for detecting biomolecules like dopamine.
• Metal oxide nanoflakes offer promising properties for electrode modification due to their high surface area and catalytic activity.

Purpose of the Study:

• To synthesize and characterize Al-ZnO nanoflakes (NFs).
• To develop a modified carbon paste electrode (MCPE) using Al-ZnO NFs for dopamine (DOA) detection.
• To evaluate the electrochemical sensor properties of the developed electrode.

Main Methods:

• Co-precipitation synthesis of ZnO and Al-ZnO NFs.
• Characterization using X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), and energy dispersive X-ray spectroscopy (EDS).
• Electrode modification with Al-ZnO NFs and electropolymerization with textile dye red DSBR.
• Electrochemical analysis of dopamine at pH 7.4.

Main Results:

• The Al-ZnO MCPE, electropolymerized with red DSBR (Po-RD/Al-ZnO MCPE), showed excellent electrochemical sensor properties for DOA.
• Optimized parameters included scan rate, pH, and DOA concentration.
• Achieved a low detection limit of 0.58 μM for dopamine.
• The sensor exhibited fast electron-transfer kinetics and good surface coverage.

Conclusions:

• The Po-RD/Al-ZnO MCPE is a stable, sensitive, selective, and reproducible sensor for electrochemical dopamine detection.
• This modified electrode holds potential for analytical applications in biological samples.