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Updated: Oct 29, 2025

Manipulation of Gene Function in Mexican Cavefish
Published on: April 22, 2019
Evolution of hemoglobin function in tropical air-breathing catfishes
Niels Christian Moth Andersen1, Angela Fago1, Christian Damsgaard1,2
1Section for Zoophysiology, Department of Biology, Aarhus University, Aarhus C, Denmark.
Abstract:
The evolution of hemoglobin function in the transition from water- to air-breathing has been highly debated but remains unresolved. Here, we characterized the hemoglobin function in five closely related water- and air-breathing catfishes. We identify distinct directions of hemoglobin evolution in the clades that evolved air-breathing, and we show strong selection on hemoglobin function within the catfishes. These findings show that the lack of a general direction in hemoglobin function in the transition from water- to air-breathing may have resulted from divergent selection on hemoglobin function in independent clades of air-breathing fishes.
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