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Multiple myeloma complicated by skull plasmacytoma discovered after head injury
Qiang Yue1, Xiaomu Ma1, Ming Feng1
1Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100010 Beijing, China.
Abstract:
Plasmacytoma is a malignant tumor originating from the plasma cells of the bone marrow. Those discovered after a head injury is rare. We report a case of a 48-year-old female who complained of scalp mass without other symptoms after head injury. Meningioma was considered preoperatively based on imaging findings, and surgical resection was performed. Postoperatively, multiple myeloma complicated by skull plasmacytoma was diagnosed by histopathology and systematic examinations in succession. When evaluating a head mass that appeared after a head injury, plasmacytoma should be considered at times. Osteolytic changes and biconvex form on imaging are beneficial to differentiation.
Insights
A rare skull plasmacytoma, a malignant plasma cell tumor, was diagnosed in a woman after a head injury. Imaging showing osteolytic changes and a biconvex form can aid in differentiating this rare condition.
Area of Science:
- Oncology
- Neurology
- Pathology
Background:
- Plasmacytoma, a rare malignant tumor of plasma cells, typically originates in the bone marrow.
- The occurrence of plasmacytoma following a head injury is exceptionally uncommon.
- Early diagnosis and differentiation are crucial for effective management of such rare presentations.
Observation:
- A 48-year-old female presented with a scalp mass subsequent to a head injury.
- Preoperative imaging suggested meningioma, leading to surgical resection.
- Post-surgery, histopathology and systemic evaluations revealed multiple myeloma with skull plasmacytoma.
Findings:
- The case highlights a rare instance of skull plasmacytoma presenting after head trauma.
- Histopathological analysis confirmed the diagnosis, distinguishing it from the initially suspected meningioma.
- Systematic examinations were essential to diagnose the underlying multiple myeloma.
Implications:
- Clinicians should consider plasmacytoma in the differential diagnosis of head masses appearing after head injury.
- Characteristic imaging findings, such as osteolytic changes and a biconvex form, can assist in differentiating plasmacytoma.
- This case underscores the importance of thorough investigation for rare oncological conditions even after seemingly minor trauma.
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