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Genetics of stomach and ocular alcohol dehydrogenase and aldehyde dehydrogenase in the mouse
R S Holmes1, R A Popp, J L VandeBerg
1Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78284.
Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement
|January 1, 1987
Abstract:
Activity variants of the stomach and ocular isozyme of aldehyde dehydrogenase (AHD-4) were observed among inbred strains of mice. The phenotypes were inherited in a normal mendelian fashion, with two alleles showing codominant expression at a single locus (Ahd-4). Linkage data indicated that Ahd-4 is localized on chromosome 11 near Hba (alpha hemoglobin locus), and segregated independently of Adh-3, encoding the stomach and ocular isozyme of alcohol dehydrogenase (ADH-C2).