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Related Experiment Video

Updated: May 8, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Published on: April 21, 2022

Multiple malignant tumors.

D N Chirila¹, N A Turdeanu, N A Constantea

¹Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania. dacianachirila@gmail.com

Chirurgia (Bucharest, Romania : 1990)

|August 21, 2013

Summary

This summary is machine-generated.

Improved cancer diagnosis and treatment lead to more patients developing multiple primary cancers. This study highlights common cancer sites and the need to consider synchronous tumors, as successful treatment doesn't prevent new ones.

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Area of Science:

Oncology
Cancer Research
Epidemiology

Background:

Advances in cancer diagnosis and therapy increase patient survival rates.
This leads to a growing number of patients developing multiple primary malignancies over time.

Purpose of the Study:

To analyze the incidence and characteristics of patients with multiple primary malignant tumors.
To identify common cancer sites in patients with synchronous or metachronous tumors.

Main Methods:

Retrospective analysis of patients diagnosed with at least two primary cancers.
Data collected from Cluj-Napoca Municipal Hospital over a 7.5-year period.

Main Results:

217 patients (4.33%) out of 5003 diagnosed with primary cancer had multiple malignancies.
Most frequent sites for multiple tumors included breast, colorectum, urinary bladder, prostate, and kidneys.

Conclusions:

The possibility of synchronous tumors must be considered in cancer patient management.
Successful treatment of one cancer does not preclude the development of a new primary malignancy.