Related Experiment Videos
The pharmacokinetics of D-penicillamine in neonates
G Oroszlán1, T Szabó, L Lakatos
1Department of Paediatrics, Debrecen University Medical School, Hungary.
Acta Paediatrica Hungarica
|January 1, 1987
Abstract:
The pharmacokinetics of D-penicillamine in premature babies was studied. The metabolism of the drug was characterized by a long half-life (115 min) with a low plasma clearance (2.84 ml/min/kg body weight) in contrast to adults. The mean volume of distribution (649/ml/kg body weight) was similar to that of adults.