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Updated: Oct 28, 2025

A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments

A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments

Published on: August 6, 2013

Recent Advances in Microfluidic Platforms for Programming Cell-Based Living Materials.

Pengchao Zhang^1,2, Ning Shao^1,2, Lidong Qin^1,2

¹Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX, 77030, USA.

Advanced Materials (Deerfield Beach, Fla.)

|July 16, 2021

Summary

This summary is machine-generated.

Microfluidic platforms enable high-throughput programming of cell-based living materials for applications in cancer therapy and regenerative medicine. This review highlights advances in microfluidic technologies for engineering diverse cell constructs, including organoids and organs.

Keywords:

cells delivery microfluidics organ chips organoids

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Last Updated: Oct 28, 2025

A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments

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Published on: August 6, 2013

Generation of Dynamical Environmental Conditions using a High-Throughput Microfluidic Device

Generation of Dynamical Environmental Conditions using a High-Throughput Microfluidic Device

Published on: April 17, 2021

A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression

A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression

Published on: October 6, 2019

Area of Science:

Biomaterials Engineering
Tissue Engineering
Microfluidics

Background:

Cell-based living materials (e.g., cells, organoids, organs) are vital for healthcare applications.
Microfluidic platforms offer high-throughput, scalable, and efficient methods for programming these materials.
Advances in materials science, microfabrication, and cell biology drive progress in this field.

Purpose of the Study:

To review recent progress in novel microfluidic platforms for programming cell-based living materials.
To introduce microfluidic platform features, categories, materials, and fabrication methods.
To highlight advances in programming single cells, cell-laden fibers, cell sheets, organoids, and organs using microfluidics.

Main Methods:

Introduction to microfluidic platform features, materials, and fabrication techniques.
Review of design principles for microfluidic platforms.
Highlighting programming strategies for various cell-based living materials.

Main Results:

Overview of microfluidic platform characteristics and fabrication.
Detailed discussion on programming single cells, cell-laden fibers, cell sheets, organoids, and organs.
Identification of recent advancements in microfluidic control over cell-based materials.

Conclusions:

Microfluidics is a powerful tool for advancing cell-based living materials.
Interdisciplinary collaboration is crucial for future development in healthcare applications.
Future trends point towards enhanced capabilities in engineering complex biological constructs.