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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

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This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
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Related Experiment Video

Updated: Oct 28, 2025

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
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Collaboration in colorectal surgical research.

Jacob Rosenberg1, Eva Angenete2, Thomas Pinkney3

  • 1Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev, Denmark.

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
|July 17, 2021
PubMed
Summary

Large surgical research collaborations can overcome decades of under-funding and under-delivery. These networks enable high-quality interventional and observational studies, providing timely, high-level evidence for clinical questions.

Keywords:
collaborationcolorectalmulti-centerrandomized controlled trialsresearchsurgery

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Area of Science:

  • Surgical research methodology
  • Clinical trial design
  • Collaborative research networks

Background:

  • Surgical research historically suffers from insufficient power, funding, and delivery.
  • This limits the ability to answer critical clinical questions effectively.
  • Existing models often fail to generate robust evidence.

Purpose of the Study:

  • To highlight the potential of large research collaborations in surgery.
  • To showcase successful models in colorectal surgery research.
  • To advocate for network-based approaches to surgical evidence generation.

Main Methods:

  • Review of experiences from established surgical research collaborations.
  • Case examples: West Midlands Research Collaborative (WMRC), Scandinavian Surgical Outcomes Research Group (SSORG), and European Society of Coloproctology.
  • Analysis of collaborative structures enabling large-scale studies.

Main Results:

  • Collaborative networks facilitate the execution of under-powered interventional trials.
  • They enable robust international observational studies with substantial patient cohorts.
  • Examples demonstrate the capacity to deliver high-quality research efficiently.

Conclusions:

  • Active research networks are crucial for advancing surgical science.
  • Collaborative models can overcome limitations of traditional surgical research.
  • These networks provide a viable pathway for generating high-level evidence to address key clinical questions.