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Could patients benefit from whole-brain radiotherapy with unilateral hippocampus sparing?

Lucas Gomes Sapienza1, Michelle S Ludwig1, Jacob J Mandel2

  • 1Department of Radiation Oncology, Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas, United States.

Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
|July 19, 2021
PubMed
Abstract

No abstract available in PubMed .

Keywords:
brain metastasishippocampusneuro-cognitive functionradiotherapy

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The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
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