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Updated: Oct 27, 2025

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The prospective GermanVasc cohort study.

Artur Kotov1, Frederik Peters1, Eike Sebastian Debus1

  • 1University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

VASA. Zeitschrift Fur Gefasskrankheiten
|July 19, 2021
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Summary
This summary is machine-generated.

The GermanVasc registry tracked 5,608 patients with symptomatic peripheral artery disease (PAD) in Germany, revealing real-world treatment patterns and patient characteristics. This study offers insights into current clinical practice for PAD management.

Keywords:
Health services researchbypass surgerychronic limb-threatening ischaemiaendovascular techniquesintermittent claudicationperipheral artery disease

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Area of Science:

  • Vascular Surgery
  • Cardiology
  • Public Health

Background:

  • Observational studies show variability in symptomatic peripheral artery disease (PAD) treatment.
  • A systematic assessment of real-world clinical practice for PAD is lacking.
  • The GermanVasc registry was established to collect comprehensive data on PAD treatment and outcomes in Germany.

Purpose of the Study:

  • To report baseline characteristics of patients prospectively enrolled in the GermanVasc registry until the end of 2020.
  • To provide insights into the real-world practice of treatment and outcomes for symptomatic PAD in Germany.

Main Methods:

  • Prospective longitudinal multicentre cohort study (GermanVasc registry).
  • Inclusion of patients undergoing invasive revascularization for chronic symptomatic PAD (May 2018 - Dec 2020).
  • Comprehensive data collection with rigorous internal and external validation.

Main Results:

  • 5,608 patients from 31 centers included; median age 69 years, 34% female.
  • 30% had chronic limb-threatening ischemia; 69% of procedures were endovascular.
  • High prevalence of comorbidities: 75% smokers, 36% diabetes, 30% ischemic heart disease.

Conclusions:

  • The GermanVasc registry offers a broad view of symptomatic PAD treatment in Germany.
  • The cohort represents diverse disease severity and intervention types, exceeding typical trial populations.
  • Future analyses will focus on comparative outcomes within this real-world cohort.