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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Updated: Oct 27, 2025

Corneal Donor Tissue Preparation for Endothelial Keratoplasty
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Corneal Donation: Current Guidelines and Future Direction.

Majid Moshirfar1,2,3, Varshini S Odayar4, Shannon E McCabe1,5

  • 1Hoopes Vision Research Center, Draper, UT, 84020, USA.

Clinical Ophthalmology (Auckland, N.Z.)
|July 21, 2021
PubMed
Summary
This summary is machine-generated.

This review covers corneal donation and eye banking practices, highlighting the impact of COVID-19 on donor availability. It explores future trends to enhance corneal transplantation efficiency and safety.

Keywords:
COVID-19cornea transplantdonor corneadonor recipienteye bankkeratoplasty

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Area of Science:

  • Ophthalmology
  • Transplantation Science
  • Public Health

Background:

  • Corneal transplantation relies on donor corneas, with established screening and preservation protocols.
  • Eye banking policies, influenced by regulatory bodies like the FDA, ensure donor suitability and prevent disease transmission.
  • Emerging infectious diseases pose new challenges to donor pool safety and availability.

Purpose of the Study:

  • To review current practices and guidelines in corneal donation and eye banking.
  • To describe the impact of COVID-19 and other emerging diseases on the corneal donor pool.
  • To discuss future trends for improving corneal donation and eye banking efficiency.

Main Methods:

  • Literature review of current practices and guidelines.
  • Analysis of the implications of emerging diseases, including COVID-19, on corneal donation.
  • Exploration of future trends and innovations in eye banking.

Main Results:

  • Global eye banks have diverse guidelines for evaluating donor cornea viability.
  • Donor age, medical history, and disease transmission risk are key screening parameters.
  • Emerging infectious diseases, such as SARS-CoV-2, present significant transmissibility risks.

Conclusions:

  • Rigorous screening, preservation, and storage are vital for safe corneal transplantation.
  • Adapting to emerging diseases is crucial for maintaining a safe and adequate donor pool.
  • Advancements like partial-thickness and lamellar keratoplasty optimize the use of donor corneas.