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Minerals

Minerals

Minerals are essential nutrients that the human body needs in small amounts to work properly. They play a vital role in many bodily functions, such as building strong bones and transmitting nerve impulses. Some minerals are needed for hormone production or to maintain a normal heartbeat. Major minerals include calcium, phosphorus, potassium, sulfur, sodium, chlorine, and magnesium, while trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride, and selenium.

Major...

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Updated: Oct 27, 2025

Analysis of Minerals Produced by hFOB 1.19 and Saos-2 Cells Using Transmission Electron Microscopy with Energy Dispersive X-ray Microanalysis

Analysis of Minerals Produced by hFOB 1.19 and Saos-2 Cells Using Transmission Electron Microscopy with Energy Dispersive X-ray Microanalysis

Published on: June 24, 2018

Topographically guided hierarchical mineralization.

X Deng^1,2, A Hasan^3,4,5, S Elsharkawy⁶

¹School of Engineering and Materials Science, Queen Mary University of London, London, E1 4NS, UK.

Materials Today. Bio

|July 21, 2021

Summary

This summary is machine-generated.

Researchers developed spatially guided mineralized structures using protein matrices and surface topographies. This biomimetic approach controls crystal alignment for advanced material design, crucial for hard tissue regeneration.

Keywords:

Bone Crystallization Dental enamel Elastin-like recombinamer Fluorapatite Hierarchical mineralization Protein-based biomineralization Surface topographies

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Last Updated: Oct 27, 2025

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Area of Science:

Materials Science
Biomaterials Engineering
Nanotechnology

Background:

Organic-inorganic hybrid materials mimic biological systems.
Controlling spatial mineralization remains a challenge in biomimetic strategies.

Purpose of the Study:

To develop spatially guided mineralized structures using protein matrices and surface topographies.
To investigate how surface topography influences nanocrystal alignment and macroscale mineralization.
To demonstrate selective control over hierarchical mineralization.

Main Methods:

Integration of protein-based mineralizing matrices with surface topographies.
Utilizing defined geometrical spaces to influence nanocrystal co-alignment.
Systematic modification of surface topographies to guide mineralization.

Main Results:

Surface topographies induced subtle changes in nanocrystal co-alignment.
These changes led to significant microscale and macroscale mineralization.
Hierarchical mineralized structures were selectively grown through topography modification.

Conclusions:

Protein-matrix and topography integration enables spatial control over mineralization.
This method allows for directed anisotropic growth of mineralized structures.
Potential applications include designing synthetic biomaterials for hard tissue repair and regeneration.