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Perspectives on Neuroscience
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From Other Journals: A Review of Recent Articles by Our Editorial Team
Tarek Alsaied1,2, Awais Ashfaq3
1Pittsburgh Children's Hospital Medical Center, Heart Institute, 3333 Burnet Avenue, Pittsburgh, PA, 45215, USA. tarek.alsaied84@gmail.com.
Insights
This review summarizes recent pediatric cardiology findings. Key updates include COVID-19 outcomes in adults with congenital heart disease and insights into Fontan-associated risks.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Disease
- Cardiovascular Surgery
Background:
- Recent advancements in pediatric cardiology require synthesis for clinical application.
- Understanding outcomes in complex congenital heart disease is crucial for patient management.
Purpose of the Study:
- To summarize recent key publications relevant to pediatric cardiologists.
- To highlight critical findings in congenital heart disease, cardiac surgery, and transplantation.
Main Methods:
- Review of recently published articles in peer-reviewed journals.
- Synthesis of findings across diverse pediatric cardiology topics.
Main Results:
- COVID-19 in adults with congenital heart disease shows no increased mortality versus the general population.
- Hepatorenal dysfunction in Fontan patients pre-transplant correlates with higher mortality.
- Abnormalities in Von Willebrand factor and angiopoietin signaling may drive pulmonary arteriovenous malformation in Glenn circulation.
- Low cardiac output post-Norwood procedure improves with higher hemoglobin and milrinone.
- Staged vs. complete repair of neonatal tetralogy of Fallot presents distinct advantages and disadvantages.
- Early repair (under 3 months) of complete atrioventricular canal shows comparable long-term outcomes.
Conclusions:
- Recent research offers critical updates on managing congenital heart disease, transplantation, and surgical outcomes.
- Evidence supports specific interventions for post-operative low cardiac output and informs repair strategies for neonatal congenital heart defects.
Abstract:
In this review, we provide a brief description of recently published articles addressing topics relevant to pediatric cardiologists. Our hope is to provide a summary of the latest articles published recently in other journals in our field. The articles address (1) outcomes for COVID-19 infection in adults with congenital heart disease which showed no increased mortality compared to the general population, (2) hepatorenal dysfunction before transplantation in patients with Fontan is associated with increased mortality, (3) abnormal Von Willebrand factor metabolism and angiopoietin signaling may contribute to pulmonary AVM formation in children with a Glenn circulation, (4) low cardiac output after the Norwood procedure which improves with higher hemoglobin and with milrionone, (5) a comparison of staged versus complete repair in neonatal tetralogy of Fallot reveiling the pros and cons of each strategy, (6) the long-term outcomes of early repair of complete atrioventricular canal show no difference in outcomes in patients who were repaired below 3 months of life.

