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Cardiac involvement in MRI in young population after COVID-19: A single tertiary center experience
Mehmet Akif Erdol1, Mustafa Bilal Ozbay2, Cagri Yayla1
1Cardiology Unit, University of Health Sciences, Ankara City Hospital, Ankara, Turkey.
Insights
Myocardial involvement is common in patients recovering from COVID-19, with nearly half showing cardiac issues. This study highlights the prevalence of cardiac complications in COVID-19 survivors.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Imaging
Background:
- COVID-19 (Coronavirus 2019) significantly impacts global health, causing widespread morbidity and mortality.
- While primarily a respiratory illness, COVID-19 affects multiple organs, including the heart, leading to diverse cardiovascular issues.
- Cardiac involvement post-COVID-19 ranges from mild myocardial injury to severe myocarditis.
Purpose of the Study:
- To evaluate the prevalence and characteristics of cardiac involvement in patients after recovering from COVID-19.
- To assess cardiac magnetic resonance (CMR) findings in relation to symptoms in post-COVID-19 patients.
- To identify potential indicators of cardiac dysfunction in recovered COVID-19 patients.
Main Methods:
- Retrospective analysis of 100 patients under 40 with confirmed COVID-19 (RT-PCR).
- Exclusion of patients with pre-existing chronic diseases.
- Cardiac magnetic resonance (CMR) imaging and symptom evaluation were performed.
Main Results:
- Cardiac involvement was detected in 49% of patients via CMR imaging.
- Patients with cardiac involvement frequently reported chest pain and/or dyspnea (84%).
- Lower left ventricular ejection fraction, stroke volume, and TAPSE were observed in patients with cardiac involvement.
Conclusions:
- Myocardial involvement is a common finding in symptomatic patients following COVID-19 infection.
- Further research is necessary to understand the long-term effects and clinical outcomes.
- Cardiac magnetic resonance imaging is crucial for detecting myocardial involvement post-COVID-19.
Background:
Coronavirus 2019 (COVID-19) causes morbidity and mortality in an increasing number of people worldwide. Although it mainly affects the respiratory system, it influences all organs, including the heart. It is associated with a broad spectrum of widespread cardiovascular problems ranging from mild myocardial injury to fulminant myocarditis. We aimed to evaluate the presence and prevalence of cardiac involvement in asymptomatic or symptomatic patients after they recovered from COVID 19 infection.
Methods:
A total of 100 consecutive patients with COVID-19 proven by reverse transcription polymerase chain reaction (RT-PCR), under 40 years of age and without any known additional chronic diseases were analyzed retrospectively for cardiac magnetic resonance (CMR) results and symptoms.
Results:
Cardiac involvement was detected in 49 out of 100 patients on CMR imaging. In the cardiac involvement group, the number of patients with chest pain and/or dyspnea was 41 (84%), which was statistically significant (p = 0.001). Twenty-four patients (47%) in the without cardiac involvement group were asymptomatic and this was also statistically significant (p = 0.001). LV ejection fraction was statistically significantly lower in the group with cardiac involvement (61% vs 66%, p = 0.001). LV stroke volume and tricuspid annular plane systolic excursion (TAPSE) were statistically significantly lower in patients with cardiac involvement (p = 0.028 and p = 0.019, respectively).
Conclusion:
Based on single center experience, myocardial involvement is common in symptomatic patients after COVID-19. More studies are needed for long-term side effects and clinical results in these patients.
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