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Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model
Published on: January 10, 2025
Abstract:
Retraction: "Effects of ebv-miR-BART7 on tumorigenicity, metastasis, and TRAIL sensitivity of non-small cell lung cancer," by Lei Wang, Li-fa Liu, Li Zhou, Fei Liao, and Ju Wang, J Cell Biochem. 2019; 10057-10068: The above article, published online on 19 December 2018 in Wiley Online Library (https://onlinelibrary.wiley.com/doi/10.1002/jcb.28289) has been retracted by agreement between the journal's Editor in Chief, Prof. Dr. Christian Behl, and Wiley Periodicals LLC. The retraction has been agreed following an investigation based on allegations raised by a third party. A detailed investigation revealed that several image elements of the experimental data were published elsewhere in a different scientific context. Thus, the editors consider the conclusions of this article to be invalid.
Insights
This study on non-small cell lung cancer was retracted due to duplicated image data. The findings regarding ebv-miR-BART7 are considered invalid.
Area of Science:
- Oncology
- Molecular Biology
- Virology
Context:
- Investigated the role of Epstein-Barr virus-encoded microRNA-BART7 (ebv-miR-BART7) in non-small cell lung cancer (NSCLC).
- Explored the potential impact of ebv-miR-BART7 on NSCLC tumorigenicity, metastasis, and sensitivity to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) therapy.
Purpose:
- To evaluate the effects of ebv-miR-BART7 on key aspects of non-small cell lung cancer progression and treatment response.
Summary:
- The article titled "Effects of ebv-miR-BART7 on tumorigenicity, metastasis, and TRAIL sensitivity of non-small cell lung cancer" has been retracted.
- Retraction was based on findings of duplicated experimental image data in different scientific contexts.
- The journal editors deemed the conclusions of the original article invalid due to the data integrity issues.
Impact:
- The retraction invalidates previous conclusions regarding ebv-miR-BART7's role in non-small cell lung cancer.
- Highlights the importance of rigorous data verification in scientific publishing.
- Underscores the need for maintaining scientific integrity in cancer research.
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