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Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
Published on: August 19, 2021
Feasibility of lateral sentinel lymph node biopsy in medullary thyroid cancer: Surrogate tool for determining
Min Jhi Kim1, Kyorim Back2, Jun-Ho Choe2
1Department of Surgery, CHA Ilsan Medical Center, Cha University School of Medicine, Goyang-si, South Korea.
Backgrounds:
This study aimed to evaluate usefulness of lateral sentinel lymph node biopsy (SLNB) in determining lateral neck dissection (LND) of patients with medullary thyroid cancer (MTC).
Methods:
Sixteen patients with MTC were enrolled in the study from January 2013 to June 2019. Intratumoral injection of technetium (Tc)-99m phytate followed by lymphoscintigraphy was performed preoperatively. Lateral sentinel lymph nodes were detected by a collimated gamma probe and underwent frozen analysis. Ipsilateral LND was performed in all patients to assess lateral LN status.
Results:
The identification rate of sentinel lymph nodes (SLNs) detected by radioisotope was 87.5% (14 of 16 patients). The sensitivity, specificity, positive predictive value, and negative predictive value of frozen analyses were 66.7%, 100%, 100%, and 91.6%, respectively. Based on final histopathology, however, the diagnostic values of lateral SLNB were all 100%.
Conclusions:
This study showed that lateral SLNB can be a promising surgical tool for decisions on LND in patients with MTC.
