Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Oct 27, 2025

Microbubble Fabrication of Concave-porosity PDMS Beads
11:52

Microbubble Fabrication of Concave-porosity PDMS Beads

Published on: December 15, 2015

8.5K

Preparation of Poly(Ionic Liquid) Microbeads via Cooling-Assisted Phase Separation Method.

Qi Lei1,2, Jia Zhao1,2, Fang He2

  • 1Research and Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen, Guangdong, 518057, China.

Macromolecular Rapid Communications
|July 21, 2021
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Inorganic Reinforced Poly(ionic liquid) Microcapsules: Confined Cooling-Assisted Phase Separation Self-Assembly and Enhanced Electroresponsive Properties.

Macromolecular rapid communications·2021
Same author

Prophylactic negative pressure wound therapy for surgical site infection in obese women undergoing cesarean section: an evidence synthesis with trial sequential analysis.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·2019
Same author

CaSR participates in the regulation of vascular tension in the mesentery of hypertensive rats via the PLC‑IP3/AC‑V/cAMP/RAS pathway.

Molecular medicine reports·2019
Same author

Developing a Versatile Shotgun Cloning Strategy for Single-Vector-Based Multiplex Expression of Short Interfering RNAs (siRNAs) in Mammalian Cells.

ACS synthetic biology·2019
Same author

Novel pathogenic mutations in disorders of sex development associated genes cause 46,XY complete gonadal dysgenesis.

Gene·2019
Same author

Myelin Oligodendrocyte Glycoprotein (MOG) Antibody Diseases in Children in Central South China: Clinical Features, Treatments, Influencing Factors, and Outcomes.

Frontiers in neurology·2019

A new cooling-assisted phase separation (CAPS) method enables simple, large-scale, non-chemical preparation of uniform poly(ionic liquid) microbeads. This method offers controlled size and high yield, applicable to various polymer microbeads.

Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Nanotechnology

Background:

  • Poly(ionic liquid) (PIL) microbeads are valuable materials.
  • Existing preparation methods often involve complex chemical processes or stabilizers.
  • A scalable and non-chemical method for uniform PIL microbead synthesis is needed.

Purpose of the Study:

  • To report a simple, large-scale, non-chemical method for preparing uniform poly(ionic liquid) microbeads.
  • To investigate the control over microbead size and preparation parameters.
  • To explore the applicability of the method to other polymer microbeads.

Main Methods:

  • Utilizing a cooling-assisted phase separation (CAPS) technique.
  • Dissolving PIL in a mixed solvent (good solvent and non-solvent) at high temperature.
Keywords:
microbeadsphysical preparationpoly(ionic liquids)

More Related Videos

Phase Diagram Characterization Using Magnetic Beads as Liquid Carriers
12:37

Phase Diagram Characterization Using Magnetic Beads as Liquid Carriers

Published on: September 4, 2015

12.6K
Mammalian Cell Encapsulation in Alginate Beads Using a Simple Stirred Vessel
10:20

Mammalian Cell Encapsulation in Alginate Beads Using a Simple Stirred Vessel

Published on: June 29, 2017

20.0K

Related Experiment Videos

Last Updated: Oct 27, 2025

Microbubble Fabrication of Concave-porosity PDMS Beads
11:52

Microbubble Fabrication of Concave-porosity PDMS Beads

Published on: December 15, 2015

8.5K
Phase Diagram Characterization Using Magnetic Beads as Liquid Carriers
12:37

Phase Diagram Characterization Using Magnetic Beads as Liquid Carriers

Published on: September 4, 2015

12.6K
Mammalian Cell Encapsulation in Alginate Beads Using a Simple Stirred Vessel
10:20

Mammalian Cell Encapsulation in Alginate Beads Using a Simple Stirred Vessel

Published on: June 29, 2017

20.0K
  • Cooling the saturated solution to induce phase separation and microbead formation without stabilizers.

    • Main Results:

    • Achieved uniform PIL microbead preparation with controllable size.
    • Demonstrated scalability up to 10 g with yields over 70% (room temperature) or 88% (0 °C).
    • Investigated the formation mechanism via light transmittance during cooling.

    Conclusions:

    • The CAPS method provides an efficient, scalable, and non-chemical route to uniform PIL microbeads.
    • Preparation parameters like PIL concentration, cooling rate, and agitation influence microbead characteristics.
    • The CAPS method shows potential for synthesizing various polymer microbeads.