Circularly permuted AsLOV2 as an optogenetic module for engineering photoswitchable peptides

Lequn Geng1, Jiaqi Shen1, Wenjing Wang1

  • 1Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA. wenjwang@umich.edu and Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA.

Chemical Communications (Cambridge, England)
|July 22, 2021
PubMed
Summary

Researchers engineered a light-sensing protein, AsLOV2, for precise control of peptides using circular permutation. This advancement enhances optogenetic tools for biological research.