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MULTIPLE-SESSION SUBTHRESHOLD MICROPULSE LASER THERAPY FOR EXUDATIVE PERIFOVEAL VASCULAR ANOMALOUS COMPLEX: A CASE
1Department of Ophthalmology, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, South Korea.
Retinal Cases & Brief Reports
|July 22, 2021
Summary
Subthreshold micropulse laser therapy effectively treated an exudative perifoveal vascular anomalous complex in a patient unresponsive to intravitreal injections. This novel approach improved visual acuity and resolved macular edema.
Area of Science:
- Ophthalmology
- Retinal Vascular Diseases
- Laser Therapy
Background:
- Exudative perifoveal vascular anomalous complex (EPVAC) is a rare retinal condition.
- Intravitreal injections are a common treatment but can be ineffective.
Observation:
- A 65-year-old woman presented with blurred vision due to EPVAC.
- Fundus examination revealed a perifoveal aneurysm with hemorrhages and exudates.
- Optical coherence tomography confirmed macular edema and an intraretinal cyst.
Findings:
- The patient received four intravitreal injections with no improvement in visual acuity or macular edema.
- Three sessions of 532-nm subthreshold micropulse laser therapy were administered.
- Following laser treatment, macular edema resolved, the lesion stabilized, and visual acuity improved.
Implications:
- Subthreshold micropulse laser therapy is a potentially safe and effective alternative for EPVAC unresponsive to conventional treatments.
- This case highlights a new therapeutic option for complex retinal vascular anomalies.

