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Polycythemia Vera Presenting as Hemorrhagic Stroke.

Krishnan Balagopal1, Aju Mathew2, Ansa Grace Koshy1

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Journal of Neurosciences in Rural Practice
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Polycythemia vera can cause hemorrhagic stroke due to high blood viscosity. Early recognition of blood count abnormalities is crucial for managing these serious neurological events.

Keywords:
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Area of Science:

  • Neurology
  • Hematology

Background:

  • Polycythemia vera (PV) presents a significant risk for vaso-occlusive events, including those affecting the central nervous system.
  • Increased blood viscosity and platelet activation in PV contribute to cerebral ischemia and hemorrhage.

Observation:

  • A 65-year-old woman experienced seizures and left-sided weakness.
  • Imaging revealed bilateral hemorrhagic infarction, and hematologic tests indicated a hyperviscous state.

Findings:

  • Genetic testing confirmed a mutation associated with polycythemia vera.
  • The patient's symptoms resolved with phlebotomy and antiplatelet therapy.

Implications:

  • This case underscores polycythemia vera as a potential cause of hemorrhagic stroke.
  • Routine evaluation of blood counts is vital for diagnosing and managing such neurological complications.