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Guide to functional mitral regurgitation: a contemporary review
1Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Cardiovascular Diagnosis and Therapy
|July 23, 2021
Summary
Functional mitral regurgitation (FMR) is increasing, often following heart attacks. This review covers current FMR evaluation and treatment strategies to improve patient outcomes.
Area of Science:
- Cardiology
- Medical Imaging
- Cardiac Surgery
Background:
- Functional mitral regurgitation (FMR) arises from left ventricular (LV) dysfunction, not primary valve disease.
- FMR prevalence is rising, projected to double in the US by 2030, significantly impacting post-myocardial infarction (MI) patients.
- High mortality rates (15-40% at 1 year) in FMR patients necessitate improved management.
Purpose of the Study:
- To provide a comprehensive review of current evaluation methods for FMR.
- To discuss evolving interventional strategies for managing significant FMR.
- To highlight advancements in imaging for FMR quantification and management.
Main Methods:
- Review of current diagnostic modalities, including echocardiography, cardiac CT, and cardiac MRI.
- Analysis of therapeutic interventions focusing on LV remodeling.
- Examination of surgical and transcatheter approaches for FMR.
Main Results:
- Echocardiography remains primary, but CT and MRI offer enhanced quantification.
- Management strategies focus on optimizing LV remodeling.
- Surgical and transcatheter interventions are increasingly utilized.
Conclusions:
- Accurate FMR assessment is crucial for timely intervention.
- Multimodality imaging aids in precise FMR evaluation and management decisions.
- Optimizing LV function and employing advanced interventions can improve FMR patient outcomes.
Keywords:
COAPTFunctional mitral regurgitation (FMR)MITRA-FRheart failure (HF)mitral clipmitral regurgitationmitral valve repair (MV repair)mitral valve replacement (MV replacement)myocardial infarction (MI)More Related Videos
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