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Pituitary corticotroph tumour with adrenocortical cells: A distinct clinicopathologic entity with unique morphology
Richard A Hickman1, John T Gionco1, Phyllis L Faust1
1Department of Pathology and Cell Biology, Columbia University Irving Medical Center and New York Presbyterian Hospital, New York, New York, USA.
Neuropathology and Applied Neurobiology
|July 23, 2021
Abstract:
We describe a rare TPIT-positive corticotroph PitNET that is admixed with SF1-positive adrenocortical cells. This dimorphous population of cells showed no colocalisation between TPIT and SF1 by immunofluorescence, and an adrenocortical choristoma was favoured. Methylation array analysis revealed a novel methylation profile in relation to other pituitary neoplasms.

