Related Experiment Video
Updated: Oct 27, 2025

10:10
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
1.6K
Primary congenital glaucoma surgery: outcomes and visual function.
Elena Gusson1, Francesca Chemello1, Rosa Longo2
1Department of Neuroscience, Biomedicine and Movement Sciences, University Of Verona, Eye Clinic, P.le L.A. Scuro 10, 37134, Verona, Italy.
International Ophthalmology
|July 23, 2021
Summary
Pediatric congenital glaucoma (PCG) outcomes vary by age at diagnosis, with infantile cases showing better visual acuity than neonatal ones. Early intervention and monitoring are crucial for managing vision impairment in children with PCG.
Area of Science:
- Ophthalmology
- Pediatric Medicine
- Genetics
Background:
- Pediatric congenital glaucoma (PCG) is a rare but severe form of childhood glaucoma.
- Long-term visual outcomes and predictive factors in PCG patients remain incompletely understood.
- Understanding visual development is critical for timely intervention and management.
Purpose of the Study:
- To evaluate long-term visual outcomes in pediatric congenital glaucoma (PCG) patients.
- To develop visual acuity curves for predicting visual function development in PCG.
- To identify factors associated with vision decline in neonatal and infantile PCG subgroups.
Main Methods:
- Retrospective review of pediatric glaucoma patient records (1996-2017).
- Data collection included visual acuities, surgical history, PCG subtype, and etiology of vision impairment.
- Statistical analyses identified factors linked to vision decline.
Main Results:
- Sixty-seven eyes from 40 patients were analyzed.
- Infantile PCG demonstrated better visual outcomes than neonatal PCG.
- Key factors associated with vision impairment included age at onset, sex, surgeries, IOP control, axial length, and corneal opacities. Amblyopia was the primary cause of visual impairment.
Conclusions:
- Visual outcomes in PCG are strongly correlated with the age at diagnosis.
- Effective intraocular pressure (IOP) control is achievable, but visual acuity often remains suboptimal.
- Referral to specialized services is vital for addressing global developmental issues and preventing further vision impairment.
Related Concept Videos
Open Angle Glaucoma: Treatment
771
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
771
Glaucoma: Overview
1000
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1000
Angle Closure Glaucoma: Treatment
899
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
899

