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Updated: Oct 27, 2025

Transcutaneous Microcirculatory Imaging in Preterm Neonates

Transcutaneous Microcirculatory Imaging in Preterm Neonates

Published on: December 31, 2015

Brain perfusion imaging in neonates.

Jérôme Baranger¹, Olivier Villemain², Matthias Wagner³

¹Department of Pediatrics, Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, Ontario, Canada; Translation Medicine Department, SickKids Research Institute, Toronto, Ontario, Canada.

Neuroimage. Clinical

|July 23, 2021

Summary

This summary is machine-generated.

Neonatal brain perfusion imaging is crucial for detecting developmental issues. Current methods have limitations, but advanced MRI and ultrasound show promise for improved diagnostic accuracy in infants.

Keywords:

Brain MRI Pediatrics Perfusion Ultrasound

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Published on: December 31, 2015

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Area of Science:

Medical Imaging
Neonatal Neurology
Cerebrovascular Physiology

Background:

Abnormal neonatal brain perfusion can lead to lasting neurodevelopmental problems.
Accurate assessment of regional and global perfusion is vital for identifying at-risk infants.
Current cerebral perfusion imaging techniques for neonates face significant challenges and limitations.

Purpose of the Study:

To review the methodologies and challenges in neonatal brain perfusion imaging.
To describe existing imaging modalities for neonatal cerebral perfusion.
To discuss future directions and advancements in the field.

Main Methods:

Review of current literature on neonatal brain perfusion imaging techniques.
Analysis of limitations and compromises of existing modalities (MRI, ultrasound, CT, NIRS, nuclear imaging).
Exploration of emerging advanced MRI and ultrasound techniques.

Main Results:

Existing neonatal brain perfusion imaging methods have inherent limitations.
Advanced MRI and ultrasound techniques show potential for enhanced diagnostic accuracy and robustness.
No single modality currently provides a perfect solution for comprehensive assessment.

Conclusions:

Neonatal cerebral perfusion imaging is essential but challenging.
Ongoing development of advanced imaging techniques is critical for improved infant neurodevelopmental outcomes.
Future research should focus on refining and validating novel imaging approaches.