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Updated: Oct 27, 2025

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement
Published on: July 29, 2013
Verification of phantom accuracy using a Monte Carlo simulation: bone scintigraphy chest phantom
Toshimune Ito1, Hirotatsu Tsuchikame2, Hajime Ichikawa3,4
1Department of Radiological, Technology, Faculty of Medical Technology, Teikyo University, 2-11-1 Kaga, Itabashi-ku, Tokyo, 173-8605, Japan. toito@med.teikyo-u.ac.jp.
Abstract:
We aimed to compare the measurement and simulation data of bone scintigraphy of a chest phantom using a Monte Carlo simulation to verify the accuracy of the simulated data. The SIM2 bone phantom was enclosed using 300 kBq/mL of technetium-99 m (99mTc) to represent the bone tumor and 50 kBq/mL of 99mTc to represent normal bone. Projection data were obtained using single-photon emission computed tomography (SPECT). Simulated projection data were constructed based on CT data. The contrast ratio, recovery coefficient (RC), % coefficient variation (CV), and power spectrum density (PSD) of each part were calculated from the reconstructed data. The contrast ratio and RC were equal between the actual and simulated data. Higher % CV values were noted for soft tissue than for normal bone. The PSD was equal for all frequency band ranges. Our results prove the utility of the Monte Carlo simulation for verifying various data using phantoms.
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