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Updated: Oct 27, 2025

Behavioral Approaches to Studying Innate Stress in Zebrafish
Published on: May 1, 2019
The role of cellular active stresses in shaping the zebrafish body axis
Rachna Narayanan1, Mario A Mendieta-Serrano1, Timothy E Saunders2
1Mechanobiology Institute, National University of Singapore, Singapore.
Abstract:
Tissue remodelling and organ shaping during morphogenesis are products of mechanical forces generated at the cellular level. These cell-scale forces can be coordinated across the tissue via information provided by biochemical and mechanical cues. Such coordination leads to the generation of complex tissue shape during morphogenesis. In this short review, we elaborate the role of cellular active stresses in vertebrate axis morphogenesis, primarily using examples from postgastrulation development of the zebrafish embryo.

