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Updated: Oct 26, 2025

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats
Published on: March 8, 2019
Multiple strokes due to pulmonary arteriovenous malformation.
Arsalan Talib Hashmi1, Asiya Batool2, Mazin O Khalid1
1Department of Cardiology, Maimonides Medical Center, 4802 10th Ave, Brooklyn, NY, USA.
Recurrent strokes can occur with absent left internal carotid artery and pulmonary arteriovenous malformations (PAVMs). Embolotherapy effectively treats PAVMs, significantly reducing stroke risk.
Area of Science:
- Cardiology
- Neurology
- Radiology
Background:
- Pulmonary arteriovenous malformations (PAVMs) create abnormal connections between pulmonary arteries and veins.
- These shunts cause extracardiac right-to-left blood flow, increasing stroke risk via paradoxical embolization.
- PAVMs are frequently hereditary and associated with hereditary hemorrhagic telangiectasias (HHT).
Observation:
- A patient presented with recurrent strokes.
- The patient had an absent left internal carotid artery (ICA).
- Transthoracic echocardiogram with bubble study revealed delayed bubbles in the left ventricle, suggesting PAVMs.
Findings:
- Computed tomography (CT) scan of the chest confirmed the diagnosis of PAVMs.
- The patient's condition involved both an absent left ICA and PAVMs.
- Percutaneous embolotherapy was identified as the primary treatment.
Implications:
- Early detection of PAVMs is crucial for stroke prevention.
- Echocardiogram with bubble study can be an initial diagnostic clue for PAVMs.
- Percutaneous embolotherapy offers a successful treatment option, reducing stroke risk in patients with PAVMs.
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