Related Experiment Video

Updated: Oct 26, 2025

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
15:43

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Published on: March 17, 2014

23.2K

Pseudomonas aeruginosa necrotizing bronchopneumonia

Ranjit I Kylat1

  • 1University of Arizona, College of Medicine, Department of Pediatrics, Tucson, Arizona, USA.

Autopsy & Case Reports
|July 26, 2021
PubMed

Insights

Extremely low birth weight infants face high infection risks. A case study highlights Pseudomonas aeruginosa

Area of Science:

  • Neonatalogy
  • Infectious Diseases
  • Microbiology

Background:

  • Extremely low birth weight (ELBW) infants possess immature immune systems, increasing susceptibility to infections.
  • Neonatal infections in ELBW infants correlate with elevated mortality, impaired growth, and adverse neurodevelopmental outcomes.
  • Pseudomonas aeruginosa (P. aeruginosa) is an uncommon but severe pathogen causing pneumonia and sepsis in ELBW neonates, often as a healthcare-associated infection (HAI).

Purpose of the Study:

  • To describe a case of P. aeruginosa infection in an ELBW infant.
  • To discuss factors contributing to the pathogenesis and multidrug resistance of P. aeruginosa in this vulnerable population.

Main Methods:

  • Case report of an extremely low birth weight infant.
  • Review of factors related to P. aeruginosa pathogenesis and antibiotic resistance.

Main Results:

  • An ELBW infant born at 26 weeks' gestation died at 13 days of life due to P. aeruginosa infection.
  • The study discusses P. aeruginosa's ability to adapt and develop antibiotic resistance.

Conclusions:

  • P. aeruginosa poses a significant threat to extremely low birth weight infants.
  • Understanding P. aeruginosa pathogenesis and resistance mechanisms is crucial for managing infections in neonatal intensive care units.

Keywords:
BronchopneumoniaCross InfectionInfant, Low Birth WeightInfant, PrematureNeonatal SepsisPseudomonas aeruginosa

More Related Videos

Pseudomonas aeruginosa Induced Lung Injury Model07:24

Pseudomonas aeruginosa Induced Lung Injury Model

Published on: October 29, 2014

18.7K
Methods for Detecting Cytotoxic Amyloids Following Infection of Pulmonary Endothelial Cells by Pseudomonas aeruginosa07:27

Methods for Detecting Cytotoxic Amyloids Following Infection of Pulmonary Endothelial Cells by Pseudomonas aeruginosa

Published on: July 12, 2018

5.7K

Related Concept Videos

Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
1.2K
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
534
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
427
Pneumonia IV: Management01:28

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
524
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
2.8K
Pneumothorax-I01:26

Pneumothorax-I

A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
646