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Scientific Discovery Games for Biomedical Research.

Rhiju Das1, Benjamin Keep2, Peter Washington3

  • 1Department of Biochemistry and Department of Physics, Stanford University, Stanford, California 94305, USA.

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Scientific discovery games (SDGs) leverage volunteers for biomedical research, yielding significant publications and innovations. These games demonstrate the power of citizen science in advancing fields from genomics to neuroscience.

Keywords:
citizen sciencecloud laboratorycrowdsourcinginteractive mediascientific discovery gamesvideo games

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Area of Science:

  • Biomedical Research
  • Citizen Science
  • Computational Biology

Background:

  • Scientific discovery games (SDGs) have gained prominence in the last decade.
  • They engage a large volunteer base, contributing to numerous scientific publications.

Purpose of the Study:

  • To review the origins and scientific output of SDGs.
  • To explore innovations and emergent properties of player communities.
  • To highlight future directions for SDGs.

Main Methods:

  • Review of scientific literature and case studies of various SDGs.
  • Analysis of scientific output across diverse research areas.
  • Examination of player community dynamics and contributions.

Main Results:

  • SDGs have produced compelling results and technical innovations in areas like molecular modeling, genomics, and neuroscience.
  • Problem-oriented games (e.g., Foldit, Eterna) and data-oriented games (e.g., EyeWire, Project Discovery) show significant impact.
  • Diverse player communities exhibit extraordinary contributions, including co-authorship on scientific papers.

Conclusions:

  • SDGs are a viable and impactful approach to biomedical research.
  • Player communities are a key asset, driving innovation and scientific output.
  • Future SDGs may integrate AI, cloud labs, and new educational models, advancing open science.