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Sexual Dysfunction in Sheehan Syndrome.

Soumita Mandal1, Pradip Mukhopadhyay2, Sujoy Ghosh2

  • 1Department of Endocrinology, R. G. Kar Medical College, Kolkata, India.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
|July 26, 2021
PubMed
Summary
This summary is machine-generated.

Sheehan syndrome (SS) frequently causes sexual dysfunction in women, with over 90% affected. This study objectively documents impaired sexual function in SS patients compared to healthy controls.

Keywords:
FSFISheehan syndromefemale sexual dysfunctionsexual function

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Area of Science:

  • Endocrinology
  • Sexual Medicine
  • Women's Health

Background:

  • Sheehan syndrome (SS) is a significant cause of hypopituitarism in developing nations.
  • Hormonal deficiencies in SS, particularly sex steroids, can lead to sexual dysfunction.
  • Sexual health is crucial for quality of life but often overlooked in women in developing countries.

Purpose of the Study:

  • To objectively document and assess sexual function in women with Sheehan syndrome.
  • To compare sexual function in women with SS to a control group of healthy women.
  • To highlight the impact of SS on female sexual health.

Main Methods:

  • Thirty-two women diagnosed with SS were evaluated using the Female Sexual Function Index (FSFI) questionnaire.
  • A control group of thirty healthy women of similar age and socioeconomic background was included for comparison.
  • SS diagnosis was confirmed using standard criteria.

Main Results:

  • A high prevalence of sexual dysfunction was observed, with 93% of sexually active SS patients scoring ≤26.55 on the FSFI.
  • Women with SS had significantly lower median total FSFI scores (20.8) compared to controls (29.05, P=.001).
  • Statistically significant differences were found in desire, arousal, lubrication, orgasm, and satisfaction, but not in pain during intercourse.

Conclusions:

  • Sexual dysfunction is highly prevalent, affecting over 90% of women with Sheehan syndrome.
  • The study provides objective evidence of widespread sexual dysfunction in SS.
  • These findings underscore the need to address sexual health in the management of SS.