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Updated: Oct 26, 2025

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Executive functioning in body dysmorphic disorder and obsessive-compulsive disorder.
Long Long Chen1,2, Oskar Flygare1,2, John Wallert1,2
1Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Executive functions (EFs) in body dysmorphic disorder (BDD) and obsessive-compulsive disorder (OCD) patients did not differ from controls. However, symptom severity correlated with performance on specific cognitive tests in both BDD and OCD groups.
Area of Science:
- Neuroscience
- Psychiatry
- Cognitive Psychology
Background:
- Body dysmorphic disorder (BDD) and obsessive-compulsive disorder (OCD) are distinct psychiatric conditions.
- Executive functions (EFs) are crucial for cognitive control and goal-directed behavior.
- Previous research on EFs in BDD and OCD has yielded mixed results.
Purpose of the Study:
- To compare executive functions (EFs) in patients with BDD and OCD against healthy controls.
- To investigate the relationship between symptom severity and EFs in BDD and OCD.
Main Methods:
- Adults with BDD (n=26), OCD (n=29), and healthy controls (n=28) completed computerized neuropsychological tests.
- Tests included spatial working memory (SWM), intra-extra-dimensional set shifting (IED), and stop signal task (SST) from the CANTAB battery.
- Performance was compared between groups and correlated with symptom severity.
Main Results:
- No significant differences in SWM, IED, or SST performance were found between BDD, OCD, and control groups.
- A weak positive correlation between symptom severity and errors on SWM and IED was observed in both BDD and OCD groups.
- A negative correlation between symptom severity and SST performance was noted in the BDD group.
Conclusions:
- Patients with BDD or OCD demonstrate comparable performance on tested executive functions to healthy controls.
- Symptom severity in BDD and OCD is associated with performance on specific executive function tasks.
- Further research is needed to clarify potential differences in EFs between BDD and OCD.
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