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A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
Published on: August 14, 2013
Laser injury to multiple retinal foci
J J Kearney1, H B Cohen, B E Stuck
1Division of Ocular Hazards, Letterman Army Institute of Research, Presidio of San Francisco, CA 94129-6800.
Lasers in Surgery and Medicine
|January 1, 1987
Summary
A young man experienced accidental retinal laser injury from a Q-switched Nd:YAG laser. Despite initial vision loss, significant recovery occurred, leaving chorioretinal scars and a preretinal membrane.
Area of Science:
- Ophthalmology
- Laser Physics
- Retinal Injury
Background:
- Accidental exposure to laser radiation can cause significant ocular damage.
- Q-switched Neodymium-doped Yttrium Aluminum Garnet (Nd:YAG) lasers are used in targeting systems and can pose a risk of accidental eye injury.
Observation:
- A 21-year-old male sustained retinal injury from a Q-switched Nd:YAG laser (1,064 nm, 10 Hz, 20 ns pulse duration, 50 mJ nominal output).
- The injury presented as retinal necrosis, subretinal hemorrhage, vitreous hemorrhage, and striate retinopathy in three foci.
- Initial visual acuity was 20/400, rapidly improving to 20/30.
Findings:
- One year post-injury, visual acuity stabilized at 20/40.
- Mature chorioretinal scars were observed.
- A preretinal membrane with macular wrinkling was evident.
Implications:
- This case highlights the potential for severe retinal damage from accidental laser exposure.
- Understanding laser parameters is crucial for predicting injury severity and prognosis.
- Long-term sequelae, including visual impairment and structural changes, necessitate ongoing monitoring.

